产品名称:PE 小鼠抗大鼠 CD80 抗体;PE Mouse Anti-Rat CD80
中文名称:PE 小鼠抗大鼠 CD80 抗体
英文名称:PE Mouse Anti-Rat CD80
PE Mouse Anti-Rat CD80 产品介绍:
Material Number: 555014 Alternate Name: B7-1 Size: 0.2 mg Concentration: 0.2 mg/ml Clone: 3H5 Immunogen: Rat HTLV-1–transformed T-cell line Lewis-S1 Isotype: Mouse (BALB/c) IgG1, κ Reactivity: QC Testing: Rat Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. PE Mouse Anti-Rat CD80 Description:
The 3H5 antibody reacts with CD80 (B7-1), a member of the Ig superfamily of transmembrane proteins. CD80, a ligand for CD28 and CD152 (CTLA-4), is one of the accessory molecules that plays an important role in T cell-B cell costimulatory interactions. CD80 is predominantly expressed on antigen-presenting cells. It can be induced on splenic B cells by in vitro polyclonal activation such as LPS treatment. 3H5 mAb is reported to block the costimulatory function of rat CD80 and to immunoprecipitate CD80 from Lewis-S1 cell lysates.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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