产品名称:Biotin 小鼠抗大鼠 CD11b 抗体;Biotin Mouse Anti-Rat CD11b
中文名称:Biotin 小鼠抗大鼠 CD11b 抗体
英文名称:Biotin Mouse Anti-Rat CD11b
Biotin Mouse Anti-Rat CD11b 产品介绍:
Material Number: 554981 Alternate Name: Integrin αM chain, Mac-1 α chain Size: 0.5 mg Concentration: 0.5 mg/ml Clone: WT.5 Immunogen: Rat neutrophils Isotype: Mouse (BALB/c) IgA, κ Reactivity: QC Testing: Rat Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.
Biotin Mouse Anti-Rat CD11b Description:
The WT.5 antibody reacts with the α subunit of Mac-1 (αMβ2, CD11b/CD18) found on neutrophils and myeloid cells, but not on lymphocytes. Mac-1 expression is rapidly upregulated on neutrophils after activation, in the same time period that CD62L (L-selectin) is shed from the cell surface. Mac-1 mediates adhesion to ICAM-1 (CD54) and C3bi. Neutrophil binding to ICAM-1 is blocked by mAb WT.5.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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