Purified NA/LE Hamster Anti-Mouse CD40

产品名称:Purified NA/LE 仓鼠抗小鼠 CD40 抗体；Purified NA/LE Hamster Anti-Mouse CD40

中文名称:Purified NA/LE 仓鼠抗小鼠 CD40 抗体

英文名称:Purified NA/LE Hamster Anti-Mouse CD40

Purified NA/LE Hamster Anti-Mouse CD40 产品介绍：

Material Number: 553721
Size: 0.5 mg
Concentration: 1.0 mg/ml
Clone: HM40-3
Immunogen: (BALB/c x NZB)F1 mouse-derived lymphoma WEHI-231
Isotype: Armenian Hamster IgM, κ
Reactivity: QC Testing: Mouse
Tested in Development: Rat
Storage Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative,
0.2µm filtered. Endotoxin level is ≤0.01 ng/µg of protein.

Purified NA/LE Hamster Anti-Mouse CD40 Description：

The HM40-3 antibody reacts with CD40, a 40-50-kDa glycoprotein expressed on B lymphocytes and other antigen-presenting cells. The
CD40 molecule has a central role in B-cell growth and differentiation. Furthermore, interactions of CD40 with its ligand, CD154, are involved
in the initiation and effector stages of cell-mediated immune responses. CD40 may be involved in the triggering of NK cells and NK-T cells.
Soluble HM40-3 antibody stimulates splenic and peritoneal B cells to proliferate in vitro. This antibody also induces spleen B cells to express
the costimulatory molecules CD80 (B7-1) and CD86 (B7-2). HM40-3 mAb has been demonstrated to inhibit the binding of soluble CD154
(gp39, CD40 Ligand) to soluble CD40 and to cell-surface CD40. This hamster mAb to a mouse leukocyte antigen has been observed to
cross-react with similar populations of Lewis, Sprague-Dawley, and LOU16 rat leukocytes.

Purified NA/LE Hamster Anti-Mouse CD40 Preparation and Storage：

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Store undiluted at 4°C.