PE Rat Anti-Mouse CD4

产品名称:PE 大鼠抗小鼠 CD4 抗体；PE Rat Anti-Mouse CD4

中文名称:PE 大鼠抗小鼠 CD4 抗体

英文名称:PE Rat Anti-Mouse CD4

PE Rat Anti-Mouse CD4 产品介绍：

Material Number: 553652
Alternate Name: L3T4
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: H129.19
Immunogen: A.TH mouse CTL clone A15.1.17
Isotype: Rat (LOU) IgG2a, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.

PE Rat Anti-Mouse CD4 Description：

The H129.19 antibody reacts with the CD4 (L3T4) differentiation antigen expressed on thymocytes, a subpopulation of mature T lymphocytes
(i.e., MHC class II-restricted T cells, including most T helper cells), and a subset of NK-T cells of all mouse strains tested. CD4 has also been
detected on pluirpotent hematopoietic stem cells, bone marrow myeloid precursors, intrathymic lymphoid precursors, and a subset of splenic
dendritic cells. CD4 is expressed on the plasma membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing
sperm. CD4 is an antigen coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells. It
participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine lck. H129.19 mAb blocks
binding of the anti-mouse CD4 mAbs Gk1.5 (Cat. No. 557307/553729) and RM4-5 (Cat. No. 553046/553047), but not RM4-4 (Cat. No.
553055) antibody. mAb H129.19 inhibits various responses of T helper cells to antigenic or mitogenic stimuli.

PE Rat Anti-Mouse CD4 Preparation and Storage：

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.