Purified NA/LE Rat Anti-Mouse CD106

产品名称:Purified NA/LE 大鼠抗小鼠 CD106 抗体；Purified NA/LE Rat Anti-Mouse CD106

中文名称:Purified NA/LE 大鼠抗小鼠 CD106 抗体

英文名称:Purified NA/LE Rat Anti-Mouse CD106

Purified NA/LE Rat Anti-Mouse CD106 产品介绍：

Material Number: 553329
Alternate Name: Vcam-1; Vascular cell adhesion molecule 1; Vascular cell adhesion protein 1
Size: 0.5 mg
Concentration: 1.0 mg/ml
Clone: 429 (MVCAM.A)
Immunogen: Mouse preadipose cell line PA6
Isotype: Rat (LEW) IgG2a, κ
Reactivity: QC Testing: Mouse
Storage Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 
0.2µm sterile filtered. Endotoxin level is ≤0.01 EU/µg (≤0.001 ng/µg) of 
protein as determined by the LAL assay.

The 429 monoclonal antibody specifically binds to both the long (~110 kDa) transmembrane-spanning form and the truncated (~47 kDa) 
GPI-linked form of vascular cell adhesion molecule-1 (VCAM-1, CD106). CD106 is constitutively expressed on bone marrow stromal cells, 
myeloid cells, and splenic dendritic cells. Its expression on endothelial cells is upregulated by inflammatory cytokines and in certain 
pathologic conditions. CD106 expression has also been detected on apoptotic thymocytes, splenocytes, and lymphoid cell lines. VCAM-1 is a 
counter-receptor for VLA-4 (α4β1 integrin) and LPAM-1 (α4β7 integrin), and the 429 antibody partially blocks VCAM-1-mediated binding 
functions. Source of the immunogen was the mouse preadipose cell line PA6.

Purified NA/LE Rat Anti-Mouse CD106 Preparation and Storage：

Store undiluted at 4°C.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
This preparation contains no preservatives, thus it should be handled under aseptic conditions.