Purified Hamster Anti-Mouse CD28

产品名称:Purified 仓鼠抗小鼠 CD28 抗体；Purified Hamster Anti-Mouse CD28

中文名称:Purified 仓鼠抗小鼠 CD28 抗体

英文名称:Purified Hamster Anti-Mouse CD28

Purified Hamster Anti-Mouse CD28 产品介绍：

Material Number: 553295
Size: 0.5 mg
Concentration: 0.5 mg/ml
Clone: 37.51
Immunogen: Mouse EL-4 (T-cell lymphoma) Cells
Isotype: Syrian Hamster IgG2, λ1
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.



Purified Hamster Anti-Mouse CD28 Description：

The 37.51 antibody reacts with CD28, which is expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T 
cells, and at even lower density on NK cells. The expression of CD28, in splenocytes and thymocytes, has been reported to increase after 
activation. CD28 transcripts are found in mast cells, and cell-surface expression of CD28 is induced upon maturation or activation of mast 
cells. It has been reported that CD28 is not expressed on some populations of intraepithelial T lymphocytes. CD28 is a costimulatory receptor; 
its ligands include CD80 (B7-1) and CD86 (B7-2). The 37.51 mAb augments proliferation and cytokine production by activated T and NK 
cells and can provide a costimulatory signal for CTL induction. There is considerable evidence that CD28 is a costimulatory receptor involved 
in many, but not all, T cell-dependent immune responses

Purified Hamster Anti-Mouse CD28 Preparation and Storage：

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Store undiluted at 4° C.