Purified NA/LE Hamster Anti-Mouse CD28

产品名称:Purified NA/LE 仓鼠抗小鼠 CD28 抗体；Purified NA/LE Hamster Anti-Mouse CD28

中文名称:Purified NA/LE 仓鼠抗小鼠 CD28 抗体

英文名称:Purified NA/LE Hamster Anti-Mouse CD28

Purified NA/LE Hamster Anti-Mouse CD28 产品介绍：

Material Number: 553294
Alternate Name: Cd28; CD28 antigen; T-cell-specific surface glycoprotein CD28
Size: 0.5 mg
Concentration: 1.0 mg/ml
Clone: 37.51
Immunogen: Mouse EL-4 (T-cell lymphoma) Cells
Isotype: Syrian Hamster IgG2, λ1
Reactivity: QC Testing: Mouse
Storage Buffer: No azide/low endotoxin: Aqueous buffered solution containing protein 
stabilizer, no preservative, 0.2µm sterile filtered. Endotoxin level is ≤0.01 
EU/µg (≤0.001 ng/µg) of protein as determined by the LAL assay.

The 37.51 antibody reacts with CD28, which is expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T 
cells, and at even lower density on NK cells. The expression of CD28, in splenocytes and thymocytes, has been reported to increase after 
activation. CD28 transcripts are found in mast cells, and cell-surface expression of CD28 is induced upon maturation or activation of mast 
cells. It has been reported that CD28 is not expressed on some populations of intraepithelial T lymphocytes. CD28 is a costimulatory receptor; 
its ligands include CD80 (B7-1) and CD86 (B7-2). The 37.51 mAb augments proliferation and cytokine production by activated T and NK 
cells and can provide a costimulatory signal for CTL induction. There is considerable evidence that CD28 is a costimulatory receptor involved 
in many, but not all, T cell-dependent immune responses.

Purified NA/LE Hamster Anti-Mouse CD28 Preparation and Storage：

Store undiluted at 4°C.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
This preparation contains no preservatives, thus it should be handled under aseptic conditions