产品名称:PE 仓鼠抗小鼠 CD6 抗体;PE Hamster Anti-Mouse CD6
中文名称:PE 仓鼠抗小鼠 CD6 抗体
英文名称:PE Hamster Anti-Mouse CD6
PE Hamster Anti-Mouse CD6 产品介绍:
Material Number: 553237 Alternate Name: VEA; Very Early Activation Antigen; AIM; Activation Induced Molecule Size: 0.2 mg Concentration: 0.2 mg/ml Clone: H1.2F3 Immunogen: Mouse Dendritic Epidermal T Cell Line Y245 Isotype: Armenian Hamster IgG1, λ3 Reactivity: QC Testing: Mouse Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.
The H1.2F3 monoclonal antibody specifically binds to CD69 (Very Early Activation antigen), an 85 kDa disulfide-linked homodimer of differentially glycosylated subunits. CD69 is a C-type lectin, most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. Its expression is rapidly induced upon activation of lymphocytes (T, B, NK, and NK-T cells), neutrophils, and macrophages. CD69 is expressed also on thymocytes that are undergoing positive selection; its role in that process is unclear. H1.2F3 mAb augments PMA-induced T-cell stimulation and IFN-γ-induced macrophage stimulation. IL-2-activated NK cells express CD69, and H1.2F3 mAb induces redirected lysis of FcR-bearing target cells by NK cells.
PE Hamster Anti-Mouse CD6 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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