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PE Hamster Anti-Mouse CD6

产品名称: PE Hamster Anti-Mouse CD6
产品型号: BD-553237
产品展商: BD Pharmingen
产品文档: 无相关文档

简单介绍

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PE Hamster Anti-Mouse CD6  的详细介绍

产品名称:PE 仓鼠抗小鼠 CD6 抗体;PE Hamster Anti-Mouse CD6

中文名称:PE 仓鼠抗小鼠 CD6 抗体

英文名称:PE Hamster Anti-Mouse CD6

PE Hamster Anti-Mouse CD6 产品介绍:

Material Number: 553237
Alternate Name: VEA; Very Early Activation Antigen; AIM; Activation Induced Molecule
Size: 0.2 mg
Concentration: 0.2 mg/ml
Clone: H1.2F3
Immunogen: Mouse Dendritic Epidermal T Cell Line Y245
Isotype: Armenian Hamster IgG1, λ3
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.





PE Hamster Anti-Mouse CD6 Description:

The H1.2F3 monoclonal antibody specifically binds to CD69 (Very Early Activation antigen), an 85 kDa disulfide-linked homodimer of 
differentially glycosylated subunits. CD69 is a C-type lectin, most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. Its 
expression is rapidly induced upon activation of lymphocytes (T, B, NK, and NK-T cells), neutrophils, and macrophages. CD69 is expressed 
also on thymocytes that are undergoing positive selection; its role in that process is unclear. H1.2F3 mAb augments PMA-induced T-cell 
stimulation and IFN-γ-induced macrophage stimulation. IL-2-activated NK cells express CD69, and H1.2F3 mAb induces redirected lysis of 
FcR-bearing target cells by NK cells. 




PE Hamster Anti-Mouse CD6 Preparation and Storage:

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.




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