产品名称:FITC 仓鼠抗小鼠 CD69 抗体;FITC Hamster Anti-Mouse CD69
中文名称:FITC 仓鼠抗小鼠 CD69 抗体
英文名称:FITC Hamster Anti-Mouse CD69
FITC Hamster Anti-Mouse CD69 产品介绍:
Material Number: 553236 Alternate Name: Very Early Activation antigen Size: 0.5 mg Concentration: 0.5 mg/ml Clone: H1.2F3 Immunogen: Mouse Dendritic Epidermal T Cell Line Y245 Isotype: Armenian Hamster IgG1, λ3 Reactivity: QC Testing: Mouse Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. FITC Hamster Anti-Mouse CD69 Description:
The H1.2F3 antibody reacts with CD69 (Very Early Activation antigen), an 85 kDa disulfide-linked homodimer of differentially glycosylated subunits. CD69 is a C-type lectin, most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. Its expression is rapidly induced upon activation of lymphocytes (T, B, NK, and NK-T cells), neutrophils, and macrophages. CD69 is expressed also on thymocytes that are undergoing positive selection; its role in that process is unclear. H1.2F3 mAb augments PMA-induced T-cell stimulation and IFN-γ-induced macrophage stimulation. IL-2-activated NK cells express CD69, and H1.2F3 mAb induces redirected lysis of FcR-bearing target cells by NK cells.
FITC Hamster Anti-Mouse CD69 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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