产品名称:FITC 大鼠抗小鼠 Vα 3.2[b,c] TCR 抗体;FITC Rat Anti-Mouse Vα 3.2[b,c] TCR
中文名称:FITC 大鼠抗小鼠 Vα 3.2[b,c] TCR 抗体
英文名称:FITC Rat Anti-Mouse Vα 3.2[b,c] TCR
FITC Rat Anti-Mouse Vα 3.2[b,c] TCR 产品介绍:
Material Number: 553219 Size: 0.25 mg Concentration: 0.5 mg/ml Clone: RR3-16 Immunogen: Mouse Cytolytic T-Cell Clone OH6 Isotype: Rat (F344) IgG2b, κ Reactivity: QC Testing: Mouse Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. FITC Rat Anti-Mouse Vα 3.2[b,c] TCR Description:
The RR3-16 antibody reacts with the Vα 3.2 T-Cell Receptor (TCR) of mice having the b (e.g., C57BL) and c (e.g., SWR, SJL, NZB, NOD) haplotypes of the Tcra gene complex, but not with TCR encoded by other members of Tcra-V3 gene subfamily. RR3-16 antibody does not react with strains having the a (e.g., A, AKR, BALB/c, CBA, C3H/He) or d (e.g., DBA/1, DBA/2, NZW) Tcra haplotypes. In addition, it has been shown that frequencies of Vα 3.2+ CD8+ T cells from homozygous H-2k/H-2k mice are moderately higher than those from heterozygous H-2k/H-2d mice, suggesting positive selection by H-2k.
FITC Rat Anti-Mouse Vα 3.2[b,c] TCR Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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