产品名称:PerCP 大鼠抗小鼠 CD4 抗体;PerCP Rat Anti-Mouse CD4
中文名称:PerCP 大鼠抗小鼠 CD4 抗体
英文名称:PerCP Rat Anti-Mouse CD4
PerCP Rat Anti-Mouse CD4 产品介绍:
Material Number: 553052 Alternate Name: L3T4 Size: 0.1 mg Concentration: 0.2 mg/ml Clone: RM4-5 Immunogen: Mouse Thymocytes (BALB/c) Isotype: Rat (DA) IgG2a, κ Reactivity: QC Testing: Mouse Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide. PerCP Rat Anti-Mouse CD4 Description:
The RM4-5 clone has been reported to react with the CD4 (L3T4) differentiation antigen expressed on most thymocytes, subpopulations of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells and immunosuppressive regulatory T cells), and a subset of NK-T cells. CD4 has also been reported to be detected on pluripotent hematopoietic stem cells, bone marrow myeloid and B-lymphocyte precursors, intrathymic lymphoid precursors, and a subset of splenic dendritic cells. CD4 has been reported to be expressed on the plasma membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm. CD4 is an antigen coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck. Purified RM4-5 mAb has been reported to block the binding of FITC-conjugated anti-mouse CD4 clones GK1.5 and H129.19, but not the RM4-4 clone
PerCP Rat Anti-Mouse CD4 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with PerCP under optimum conditions, and unconjugated antibody and free PerCP were removed. Storage of PerCP conjugates in unoptimized diluent is not recommended and may result in loss of signal intensity. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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