APC Rat Anti-Mouse CD4

产品名称:APC 大鼠抗小鼠 CD4 抗体；APC Rat Anti-Mouse CD4

中文名称:APC 大鼠抗小鼠 CD4 抗体

英文名称:APC Rat Anti-Mouse CD4

APC Rat Anti-Mouse CD4 产品介绍：

Material Number: 553051
Alternate Name: L3T4
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: RM4-5
Immunogen: Mouse Thymocytes (BALB/c)
Isotype: Rat (DA) IgG2a, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.

The RM4-5 clone has been reported to react with the CD4 (L3T4) differentiation antigen expressed on most thymocytes, subpopulations of 
mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells and immunosuppressive regulatory T cells), and a 
subset of NK-T cells. CD4 has also been reported to be detected on pluripotent hematopoietic stem cells, bone marrow myeloid and 
B-lymphocyte precursors, intrathymic lymphoid precursors, and a subset of splenic dendritic cells. CD4 has been reported to be expressed on 
the plasma membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm. CD4 is an antigen coreceptor 
on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation through its 
association with the T-cell receptor complex and protein tyrosine kinase lck. Purified RM4-5 mAb has been reported to block the binding of 
FITC-conjugated anti-mouse CD4 clones GK1.5 and H129.19, but not the RM4-4 clone.

APC Rat Anti-Mouse CD4 Preparation and Storage：

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.