产品名称:FITC 小鼠抗人 CD138 抗体;FITC Mouse Anti-Human CD138
中文名称:FITC 小鼠抗人 CD138 抗体
英文名称:FITC Mouse Anti-Human CD138
FITC Mouse Anti-Human CD138 产品介绍:
Material Number: 552723 Alternate Name: Syndecan-1 Size: 100 tests Vol. per Test: 20 µl Clone: MI15 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: VI BP100, B005 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. FITC Mouse Anti-Human CD138 Description:
Reacts with CD138 (Syndecan-1), an 85-92 kDa single chain transmembrane protein, strongly expressed on multiple-myeloma-derived cell lines and malignant plasma cell populations. It is also expressed on pre-B cells, immature B cells, and plasma cells, but not on mature circulating B-lymphocytes. Syndecan-1 is a member of the family of transmemrane heparan sulfate proteoglycans. It is also expressed on some non-hematopoietic cells, including embryonic mesenchymal cells, vascular smooth muscle cells, endothelial and neural cells. CD138 binds to many extracellular matrix proteins through its heparan sulfate side-chains, like fibronectin, collagen types I, III, and V, tenascin, thrombospondin, and antithrombin III. It is considered an extracellular matrix receptor that may serve as a co-receptor for fibroblast growth factor and related molecules. Monoclonal antibody MI15 blocks the binding of clone B-B4 but not clone DL-101 (other anti-syndecan-1 antibodies) by flow cytometric analysis.
FITC Mouse Anti-Human CD138 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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