APC-Cy™7 Rat Anti-Mouse CD4

产品名称:APC-Cy™7 大鼠抗小鼠 CD4 抗体；APC-Cy™7 Rat Anti-Mouse CD4

中文名称:APC-Cy™7 大鼠抗小鼠 CD4 抗体

英文名称:APC-Cy™7 Rat Anti-Mouse CD4

APC-Cy™7 Rat Anti-Mouse CD4 产品介绍：

Material Number: 552051
Alternate Name: L3T4
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: GK1.5
Immunogen: Mouse CTL clone V4
Isotype: Rat (LEW) IgG2b, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.


APC-Cy™7 Rat Anti-Mouse CD4 Description：

The GK1.5 clone has been reported to react with the CD4 (L3T4) differentiation antigen expressed on most thymocytes, a subpopulation of mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells), and a subset of NK-T cells. In addition, CD4 has also been reported to be detectable on pluripotent hematopoietic stem cells, bone marrow myeliod and B-lymphocyte precursors, intrathymic lymphoid precursors, and a subset of splenic dendritic cells. CD4 has also been reported to be expressed on the plasma membrane of mouse egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm. CD4 is an antigen coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck. GK1.5 mAb reportedly blocks binding of the RM4-5  and H129.19 , but not RM4-4 antibodies. 

APC-Cy™7 Rat Anti-Mouse CD4 Preparation and Storage：

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with APC-Cy7 under optimum conditions, and unconjugated antibody and free APC-Cy7 were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.