产品名称:PE-Cy™5 小鼠抗人 CD58 抗体;PE-Cy™5 Mouse Anti-Human CD58
中文名称:PE-Cy™5 小鼠抗人 CD58 抗体
英文名称:PE-Cy™5 Mouse Anti-Human CD58
PE-Cy™5 Mouse Anti-Human CD58 产品介绍:
Material Number: 551399 Alternate Name: LFA-3 Size: 100 tests Vol. per Test: 20 µl Clone: 1C3 (AICD58.6) Isotype: Mouse IgG2a, κ Reactivity: QC Testing: Human Tested in Development: Dog Workshop: V S029 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Reacts with a 60-70 kDa membrane glycoprotein member of the immunoglobulin superfamily. CD58, also referred to as the lymphocyte function-associated antigen-3 (LFA-3), has a wide tissue distribution, being expressed on both hematopoietic and non-hematopoietic cells, including endothelial cells and fibroblasts. There are two isoforms of CD58: a glycosylphosphatidylinositol (GPI)-linked formed and a transmembrane form. Both isoforms may be expressed in the same cell type. Erythrocytes, however, only have the GPI-linked isoform. CD58 interacts with CD2 during cell adhesion. This binding can enhance antigen-specific T-cell activation.
PE-Cy™5 Mouse Anti-Human CD58 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with PE-Cy5 (formerly known as BD Cy-Chrome™) under optimum conditions, and unconjugated antibody and free PE-Cy5 were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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