产品名称:FITC 小鼠抗人 CD77 抗体;FITC Mouse Anti-Human CD77
中文名称:FITC 小鼠抗人 CD77 抗体
英文名称:FITC Mouse Anti-Human CD77
FITC Mouse Anti-Human CD77 产品介绍:
Material Number: 551353 Size: 100 tests Vol. per Test: 20 µl Clone: 5B5 Isotype: Mouse IgM, κ Reactivity: QC Testing: Human Workshop: VI CD77.5 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide. FITC Mouse Anti-Human CD77 Description:
Reacts with CD77, a small neutral glycosphingolipid, 1 kDa, also referred to as globotriaosylceramide (Gb3). CD77 is expressed on a subset of germinal center B-lymphocytes and not on peripheral blood lymphocytes, bone marrow or spleen. It has been described as a receptor for Shiga Toxin, produced by Shigella dysenteriae, and Verotoxin 1 (VT1), produced by some strains of E. coli. CD19 has been reported as a ligand for CD77 and these interaction functions in adhesion and signal transduction at a specific stage of B cell development. Studies have shown that cross-linking CD77 induces apoptosis in some B cell lines.
FITC Mouse Anti-Human CD77 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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