FITC Mouse Anti-Human HLA-A2

产品名称:FITC 小鼠抗人 HLA-A2 抗体；FITC Mouse Anti-Human HLA-A2

中文名称:FITC 小鼠抗人 HLA-A2 抗体

英文名称:FITC Mouse Anti-Human HLA-A2

FITC Mouse Anti-Human HLA-A2 产品介绍：

Material Number: 551285
Size: 0.1 mg
Concentration: 0.5 mg/ml
Clone: BB7.2
Isotype: Mouse IgG2b, κ
Reactivity: QC Testing: Human
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.

The monoclonal antibody BB7.2 reacts with a subunit of the human leukocyte antigen-A2 (HLA-A2), a class I molecule of the major 
histocompatibility complex (MHC). The MHC gene locus encodes a group of highly polymorphic, cell-surface proteins that play a broad role 
in the immune response to protein antigens. MHC molecules function by binding and presenting small antigenic protein fragments to 
antigen-specific receptors expressed by T cells (TCR). Human (human leukocyte antigen/HLA) MHC molecules comprise two major classes, 
MHC class I and class II. Functionally, class I MHC molecules can bind peptides derived from intracellular antigens (eg, viral and some 
bacterial antigens) that are specifically recognized by CD8+ T cells, and class II MHC molecules recognize antigens derived from pathogens 
multiplying in intracellular vesicles, and those derived from ingested extracellular bacteria. When presented on the cell surface by the MHC 
class II molecules, these antigens are recognized by CD4+ T cells. TCR recognize both processed peptides bound to MHC, as well as regions 
of the MHC molecule itself. CD4 and CD8 accessory molecules strengthen formation of the TCR-MHC complex through their interaction 
with non-polymorphic regions of the MHC molecule.

FITC Mouse Anti-Human HLA-A2 Preparation and Storage：

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.