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APC Mouse Anti-Human CD137

产品名称: APC Mouse Anti-Human CD137
产品型号: BD-550890
产品展商: BD Pharmingen
产品文档: 无相关文档

简单介绍

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APC Mouse Anti-Human CD137  的详细介绍

产品名称:APC 小鼠抗人 CD137 抗体;APC Mouse Anti-Human CD137

中文名称:APC 小鼠抗人 CD137 抗体

英文名称:APC Mouse Anti-Human CD137

APC Mouse Anti-Human CD137 产品介绍:

Material Number: 550890
Alternate Name: 4-1BB
Size: 100 tests
Vol. per Test: 20 µl
Clone: 4B4-1
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Workshop: VI C-7
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.




APC Mouse Anti-Human CD137 Description:

Reacts with 4-1BB, a 30 kDa glycoprotein expressed on activated T cells. 4-1BB can be detected on Con A or PHA-stimulated peripheral 
blood T cells (CD4+ and CD8+) and on CEM cells (human T-cell leukemia) following 2 day PMA and ionomycin stimulation, but not on 
resting T cells. 4-1BB is reported to be a participant in T-cell activation, being responsible for rescuing T cells from activation-induced 
apoptosis, upregulation of Th1-type, T-helper cells, downregulation of Th2-type cytokine production, and induction of cell adhesion to 
fibronectin. 

APC Mouse Anti-Human CD137 Preparation and Storage:

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.




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