产品名称:APC 小鼠抗人 CD137 抗体;APC Mouse Anti-Human CD137
中文名称:APC 小鼠抗人 CD137 抗体
英文名称:APC Mouse Anti-Human CD137
APC Mouse Anti-Human CD137 产品介绍:
Material Number: 550890 Alternate Name: 4-1BB Size: 100 tests Vol. per Test: 20 µl Clone: 4B4-1 Isotype: Mouse IgG1, κ Reactivity: QC Testing: Human Workshop: VI C-7 Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Reacts with 4-1BB, a 30 kDa glycoprotein expressed on activated T cells. 4-1BB can be detected on Con A or PHA-stimulated peripheral blood T cells (CD4+ and CD8+) and on CEM cells (human T-cell leukemia) following 2 day PMA and ionomycin stimulation, but not on resting T cells. 4-1BB is reported to be a participant in T-cell activation, being responsible for rescuing T cells from activation-induced apoptosis, upregulation of Th1-type, T-helper cells, downregulation of Th2-type cytokine production, and induction of cell adhesion to fibronectin.
APC Mouse Anti-Human CD137 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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